Discussion of imalsogreg's comment: > However, it is unknown whether dopamine neuron prediction error signaling and cue-reward learning are causally linked. The more interesting question is whether 'prediction error signalling' is a good description for the role of this spiking pattern in the first place. It's not surprising that behavior is causally linked to DA neuron manipulation. The hole in the literature that the authors refer to in the intro is still a tacit assumption in this study, not something that got experimentally evaluated.